The primary premise of M22-A3 is to reduce the burden of redundant testing. It identifies specific media of "proven reliability" for which users do not need to perform additional retesting if the manufacturer's quality control (QC) practices meet established criteria.
The full document is available in electronic PDF format from various official standards retailers. Go to product viewer dialog for this item. CLSI M22-A3 (R2018)
It applies to all commercial media regardless of packaging, such as plates, tubes, or bottles. Major Updates in the Third Edition (A3) clsi m22a3 pdf
Quality Control for Commercially Prepared Microbiological Culture Media
It explicitly defines the roles of the manufacturer, distributor, and end-user laboratory. The primary premise of M22-A3 is to reduce
The acceptable failure rate cutoff for exempting media was increased from 0.3% to 0.5% .
Cracked petri dishes, unequal filling, or hemolysis in blood agars. Go to product viewer dialog for this item
Focus on visual inspection and documentation of media upon receipt rather than full organism-based retesting for "exempt" media.
Quality Control for Commercially Prepared Microbiological Culture Media; Approved Standard, M22A3E, Published by CLSI, 2004-06-20 Go to product viewer dialog for this item. CLSI M22-A3-2004 (R2016)
M22-A3 introduced several significant changes from the previous M22-A2 version based on extensive surveys by the :